Development of DNA assembly in microfluidic devices

There is a rapidly growing demand for efficient, scalable solutions in DNA synthesis and manipulation, with potential applications in medicine, agriculture, and synthetic biology, making it a pivotal area of research and development. Microfluidic systems provide an appealing solution as they offer unprecedented precision and efficiency in biochemical processes. 
Here, we aim to develop a microfluidic device that can drastically enhance the speed and accuracy of DNA assembly, a critical step in genetic engineering. The device will perform the assembly of small fragments into a larger one and isolate the complete sequence from truncated fragments. 

We are looking for a student interested in designing and fabricating the device using rapid prototyping, optimizing the assembly and fragment separation off-chip, transpose the process to a microfluidic device and obtain the figures of merits of the integrated method. 
 
Techniques to be learned: DNA assembly, electrophoresis, microfluidics. 

Type of Project: Internship 

Master's degree: Master of Engineering Technology; Master of Science; Master of Engineering Science; Master of Bioengineering 

Duration: 6 -12 month 

Supervisor: Liesbet Lagae (Physics, Nano)

For more information or application, please contact Camila Dalben Madeira Campos (camila.campos@imec.be)

Imec allowance will be provided for students studying at a non-Belgian university.